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Mitochondrial Maturation in Human Pluripotent Stem Cell Derived Cardiomyocytes

1 Jan 2017

Abstract excerpt

Human pluripotent stem cells derived cardiomyocytes (PSC-CMs) have been widely used for disease modeling, drug safety screening, and preclinical cell therapy to regenerate myocardium. Most studies have utilized PSC-CM grown in vitro for a relatively short period after differentiation. These PSC-CMs demonstrated structural, electrophysiological, and mechanical features of primitive cardiomyocytes. A few studies...

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PMID: 28421116
DOI: 10.1155/2017/5153625

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