Article

Metadomain and metaloop genome interactions in mammalian T cells

2025-09-21

Abstract excerpt

<h4>Summary</h4> Recent studies have advanced our understanding of chromosomal organization and its principal role in gene regulation. However, most analyses have focused on short-range interactions (<2 Mb), limiting insight into broader regulatory architecture. In particular, the relationships between topologically associating domains (TADs), sub-TAD loops, long-range cross-TAD interactions, and higher-order chr...

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Literature Corpus work: 7565fed3-c932-5792-9cda-4ab370c617fa
DOI: 10.1101/2025.09.19.677419

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