Article

Generalized and specific whole-brain white matter abnormalities in human cocaine and heroin use disorders

2022-03-22

Abstract excerpt

Neuroimaging studies in substance use disorder have shown widespread impairments in white matter (WM) microstructure suggesting demyelination and axonal damage. However, substantially fewer studies explored generalized vs. acute/specific drug effects on WM. Our study assessed whole-brain WM integrity in three subgroups of addicted individuals, encompassing cocaine (CUD) and heroin (HUD) use disorder, compared to h...

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Literature Corpus work: 752e668f-e782-5184-bce1-77e20e09b9d9
DOI: 10.1101/2022.03.22.22272765

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