Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Unveiling causal relationship between white matter tracts and psychiatric disorders

14 Aug 2025

Abstract excerpt

White matter tracts (WMTs), which mediate information transmission in the brain, are closely associated with the pathogenesis of psychiatric disorders, yet the causality of their associations remain unclear. Thus, we employed two-sample bidirectional Mendelian randomization to explore the causality between WMTs and 10 psychiatric disorders. We found that one standard deviation changes of WMTs metrics modified...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Advanced MRI Techniques and Applications
Share to Advanced Neuroimaging Techniques and Applications
Share to Functional Brain Connectivity Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40813898
DOI: 10.1038/s42003-025-08669-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Unveiling causal relationship between white matter tracts and psychiatric disordersPMID 40813898Read ↗

Mendelian randomization studies of brain MRI yield insights into the pathogenesis of neuropsychiatric disordersSemantic proximity Read ↗

Mendelian randomization analyses support causal relationships between brain imaging-derived phenotypes and risk of psychiatric disorders.Semantic proximity Read ↗

Mendelian randomization analyses reveal causal relationships between brain functional networks and risk of psychiatric disorders.Semantic proximity Read ↗

Investigating Bidirectional Causal Relationships Between Imaging-Derived Brain Phenotypes and Sedative-Hypnotic Use Disorder: A Mendelian Randomization Study.Semantic proximity Read ↗

Bidirectional Mendelian randomization study of causal associations between white-matter structural connectivity and multiple sclerosis.Semantic proximity Read ↗

Genetic architecture of the white matter connectome of the human brainSemantic proximity Read ↗

Genetic architecture of the white matter connectome of the human brainSemantic proximity Read ↗

Causal associations between iron levels in subcortical brain regions and psychiatric disorders: a Mendelian randomization studySemantic proximity Read ↗

Unraveling the causal relationships between depression and brain structural imaging phenotypes: A bidirectional Mendelian Randomization study.Semantic proximity Read ↗

Transdiagnostic impairments in white matter integrity across the Psychosis Continuum: a systematic review and meta-analysis of diffusion studiesSemantic proximity Read ↗

Deriving Mendelian Randomization-Based Causal Networks of Brain Imaging Phenotypes and Bipolar Disorder.Semantic proximity Read ↗

Diffusion Basis Spectrum Imaging of White Matter in Schizophrenia and Bipolar DisorderSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.