Article

Brain Structure and Substance Use: Disentangling Risk, Exposure, and Drug-Specific Effects

2026-03-23

Abstract excerpt

<h4>Importance</h4> Polysubstance use is common, but substance use associations with neuroimaging measures have largely been investigated within individual drug types. Whether effects are substance-specific or -general, and how predispositional risk and exposure contribute, remains unclear. <h4>Objective</h4> Identify shared and unique associations between substance use and brain structure, and characterize the...

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Literature Corpus work: 8ccb8028-b67e-54b5-98bb-28b1f8a71a2c
DOI: 10.64898/2026.03.20.26348897

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