Back to search

Article

Incidence and associated risk factors of antituberculosis drug induced hepatotoxicity among TB patients

2025-05-15

Abstract excerpt

<title>Abstract</title> <p>Background Tuberculosis (TB) is a global health challenge. Use of anti-TB drugs to treat TB is associated with high prevalence of side effects and unpredictable clinical hepatotoxicity that include anti-TB drug induced liver injury (ATDILI). The aim of this study was to determine the incidence and associated clinical risk factors of ATDILI among South African patients with TB infection...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
75080bfe-d839-5529-8bf2-5694d4eb5325
DOI
10.21203/rs.3.rs-6596752/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Incidence and associated risk factors of antituberculosis drug induced hepatotoxicity among TB patientsDOI 10.21203/rs.3.rs-6596752/v1
Antituberculosis Drug-Induced Adverse Events in the Liver, Kidneys, and Blood: Clinical Profiles and Pharmacogenetic Predictors.Semantic proximity
Pharmacogenetic & pharmacokinetic biomarker for efavirenz based ARV and rifampicin based anti-TB drug induced liver injury in TB-HIV infected patients.Semantic proximity
NAT2 Acetylation Status Predicts Hepatotoxicity During Antituberculosis Therapy: Cumulative Risk Analysis of a Multiethnic CohortSemantic proximity
Genome-wide association and replication study of anti-tuberculosis drugs-induced liver toxicitySemantic proximity
The role of NAT2 genetic variants in anti-tuberculosis drug-induced liver injury (AT-DILI): a meta-analysis.Semantic proximity
Assessment of Pharmacotherapy and Clinical Outcomes of Treatment for the Development of Cardiovascular Disease among Tuberculosis PatientsSemantic proximity
Genome-Wide Association and Replication Study of Hepatotoxicity Induced by Antiretrovirals Alone or with Concomitant Anti-Tuberculosis Drugs.Semantic proximity
Prospective study of ALDH1A1 gene polymorphisms associated with antituberculosis drug-induced liver injury in western Chinese Han population.Semantic proximity
NR1I2 genetic polymorphisms and the risk of anti-tuberculosis drug-induced hepatotoxicity: A systematic review and meta-analysis.Semantic proximity
Association of POR and PPARα polymorphisms with risk of anti-tuberculosis drug-induced liver injury in Western Chinese Han population.Semantic proximity
Genetic polymorphisms and adverse reactions to antituberculosis therapySemantic proximity
Relevance of NAT2 genotype and clinical factors to risk for antituberculosis drug-induced liver injury.Semantic proximity
Select a neighboring publication to make it the new centre.