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Antituberculosis Drug-Induced Adverse Events in the Liver, Kidneys, and Blood: Clinical Profiles and Pharmacogenetic Predictors.

Clinical pharmacology and therapeutics - 1 Aug 2018

Hu Xuejiao, Zhang Mei, Bai Hao, Wu Lijuan, Chen Yanqing, Ding Liu, Zhao Zhenzhen, Peng Wu, Liu Tangyuheng, Song Jiajia, Li Yinyu, Lu Xiaojun, Chen Xuerong, Zhou Yanhong, Ying Binwu

Abstract excerpt

Antituberculosis drug-induced adverse drug reactions (ATD-ADRs) are increasing globally, and it is key to identify candidate ATD-ADRs loci for clinical management. We prospectively enrolled 1,235 highly suspicious tuberculosis (TB) inpatients to investigate the profiles and genetic risk factors of ATD-ADRs in the liver, kidneys, and blood. Overall, 644 subjects were eligible and genotyped for seven polymorphisms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29071720
DOI: 10.1002/cpt.924
PMCID: PMC6099196

Genes

NUDT15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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