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Article

NR1I2 genetic polymorphisms and the risk of anti-tuberculosis drug-induced hepatotoxicity: A systematic review and meta-analysis.

Pharmacology research & perspectives - 1 Dec 2020

Yang Miaomiao, Qiu Yunliang, Jin Yanyu, Liu Wenpei, Wang Qingliang, Yi Honggang, Tang Shaowen

Abstract excerpt

Anti-tuberculosis drug-induced hepatotoxicity (ATDH) is a serious adverse drug reaction. Conflicting results have been obtained regarding the associations of nuclear receptor subfamily 1 group I member 2 (NR1I2) gene polymorphisms on susceptibility to ATDH. Therefore, we aimed to evaluate the associations using a systematic review/meta-analysis approach. PubMed, Medline, Cochrane Library, Web of Science and...

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Identifiers

PMID: 33300686
DOI: 10.1002/prp2.696
PMCID: PMC7726956

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