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Article

Association of POR and PPARα polymorphisms with risk of anti-tuberculosis drug-induced liver injury in Western Chinese Han population.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Apr 2020

Zhang Chunying, Jiao Lin, Bai Hao, Zhao Zhenzhen, Hu Xuejiao, Wang Minjin, Wu Tao, Peng Wu, Liu Tangyuheng, Song Jiajia, Zhou Juan, Li Mengjiao, Lyv Mengyuan, Zhang Jingwei, Chen Hao, Chen Jie, Ying Binwu

Abstract excerpt

OBJECTIVES: Anti-tuberculosis drug-induced liver injury (ATDILI) is a common and sometimes severe adverse drug reaction (ADR). This study was conducted to investigate the relationship between polymorphisms of two genes, cytochrome P450 oxidoreductase (POR) and peroxisome proliferator-activated receptor α (PPARα), and the risk of ATDILI in Western Chinese Han population. METHODS: A total of 118 tuberculosis (TB)...

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Identifiers

PMID: 31857256
DOI: 10.1016/j.meegid.2019.104147

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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