Article

Identification of INSR protein structural differences in Diabetes Mellitus type 2 subjects from protein sequences

2021-08-17

Abstract excerpt

In this paper, we constructed several models of the Insulin Receptor protein(abbreviated INSR) from protein sequences from pathogenic and benign variants of type 2 Diabetes Mellitus patients. Through modeling these variants, we were able to determine which sections of the tertiary structure of the INSR protein were linked to type 2 Diabetes Mellitus. Ultimately, we created a map of the INSR protein and indicated w...

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Literature Corpus work: 74f5130f-0a4c-5003-9fab-078255071252
DOI: 10.1101/2021.08.17.456584

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