Article

In Silico Analysis of Effect of Non-synonymous SNPs associated with Permanent Neonatal Diabetes Mellitus on Stability and Structure of Human Insulin

2020-09-02

Abstract excerpt

<h4>Motivation</h4> Proteins are the building-blocks of life. However with the deluge of data on protein sequences and their association with diseases, it is imperative to use computational tools to aid experimental analysis. Determination of the impact of disease-causing SNPs on protein’s structure is crucial in discovering how a disease affects the functions on a fundamental level and thereafter, determining po...

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Literature Corpus work: f312b0be-4093-5b4a-9e9c-62875a74e71e
DOI: 10.1101/2020.09.01.278002

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