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Article

INS-gene mutations: from genetics and beta cell biology to clinical disease.

Molecular aspects of medicine - 1 Apr 2015

Liu Ming, Sun Jinhong, Cui Jinqiu, Chen Wei, Guo Huan, Barbetti Fabrizio, Arvan Peter

Abstract excerpt

A growing list of insulin gene mutations causing a new form of monogenic diabetes has drawn increasing attention over the past seven years. The mutations have been identified in the untranslated regions of the insulin gene as well as the coding sequence of preproinsulin including within the signal peptide, insulin B-chain, C-peptide, insulin A-chain, and the proteolytic cleavage sites both for signal peptidase...

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Source

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Identifiers

PMID: 25542748
DOI: 10.1016/j.mam.2014.12.001
PMCID: PMC4404187

Genes

INS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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