Article

Interaction studies of risk proteins in human induced neurons reveal convergent biology and novel mechanisms underlying autism spectrum disorders

2021-10-10

Abstract excerpt

Sequencing studies of autism spectrum disorders (ASDs) have identified numerous risk genes with enriched expression in the human brain, but it is still unclear how these genes converge into cell type-specific networks and how their encoded proteins mechanistically contribute to ASDs. To address this question, we performed brain cell type-specific interaction proteomics to build a protein-protein interaction networ...

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Literature Corpus work: 74f3e7bc-6cf5-52bf-83c1-078e0c4db708
DOI: 10.1101/2021.10.07.21264575

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