Article

Convergence and Divergence of Common and Rare Variants of Autism Spectrum Disorders in Tissue-specific Pathways and Gene Networks

2025-05-15

Abstract excerpt

<title>Abstract</title> <p> The genetic heterogeneity of autism spectrum disorder (ASD) presents significant challenges in understanding its pathogenic mechanisms, as the genetic risk involves numerous common variants and rare <italic>de novo</italic> or inherited variants. Prior research has mainly focused on identifying rare variants and their impact on neurodevelopment and neuronal functions in cortical bra...

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Literature Corpus work: 8d02bad0-3074-5554-a20e-f006f9151821
DOI: 10.21203/rs.3.rs-6581159/v1

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