Article
Multiplex gene and phenotype network to characterize shared genetic pathways of epilepsy and autism.
Scientific reports - 13 Jan 2021
Peng Jacqueline, Zhou Yunyun, Wang Kai
Abstract excerpt
It is well established that epilepsy and autism spectrum disorder (ASD) commonly co-occur; however, the underlying biological mechanisms of the co-occurence from their genetic susceptibility are not well understood. Our aim in this study is to characterize genetic modules of subgroups of epilepsy and autism genes that have similar phenotypic manifestations and biological functions. We first integrate a large...
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