Article

Autism genetics perturb prenatal neurodevelopment through a hierarchy of broadly-expressed and brain-specific genes

2020-05-26

Abstract excerpt

<h4>ABSTRACT</h4> Numerous genes are associated with autism spectrum disorder (ASD); however, it remains unclear how most ASD risk genes influence neurodevelopment and result in similar traits. Recent genetic models of complex traits suggest non-tissue-specific genes converge on core disease genes; so we analyzed ASD genetics in this context. We found ASD risk genes partition cleanly into broadly-expressed and br...

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Identifiers and source

Literature Corpus work: 3129dadf-8880-53bd-9e2a-2d9d601796c0
DOI: 10.1101/2020.05.23.112623

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