Article

Modulation of cannabinoid receptor 2 alters neuroinflammation and reduces formation of alpha-synuclein aggregates in a rat model of nigral synucleinopathy

2023-08-27

Abstract excerpt

<h4>ABSTRACT</h4> Research into the disequilibrium of microglial phenotypes has become an area of intense focus in neurodegenerative disease as a potential mechanism that contributes to chronic neuroinflammation and neuronal loss in Parkinson’s disease (PD). There is growing evidence that neuroinflammation accompanies and may promote progression of alpha-synuclein (Asyn)-induced nigral dopaminergic (DA) degenerat...

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Literature Corpus work: 74d9ffba-68ce-5b78-904e-e643922b2f2a
DOI: 10.1101/2023.08.25.554814

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