Article

Genes with Specificity for Expression in the Round Cell Layer of the Growth Plate are Enriched in GWAS of Human Height

2021-02-24

Abstract excerpt

<h4>ABSTRACT</h4> Human adult height reflects the outcome of childhood skeletal growth. Growth plate (epiphyseal) chondrocytes are key determinants of height. As epiphyseal chondrocytes mature and proliferate, they pass through three developmental stages, which are organized into three distinct layers in the growth plate: 1) resting (round), 2) proliferative (flat), and 3) hypertrophic. Recent genome-wide associa...

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Literature Corpus work: 7470aa20-48f5-566e-be17-001d32eead09
DOI: 10.1101/2021.02.24.432568

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