Article

Human growth plates house resting zone sub-populations with features of quiescent stem cells

2025-03-14

Abstract excerpt

<h4>ABSTRACT</h4> Incomplete mapping of gene expression within human (epiphyseal) growth plates contributes to the challenges of diagnosing and treating patients with skeletal growth disorders. To address this issue, we applied spatially resolved transcriptomics to rare growth plate biopsies obtained from healthy adolescents. In addition to identifying novel markers of each zone of the human growth plate, spatial...

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Literature Corpus work: 1bf95805-712a-5a18-8d1e-0cd6c7449363
DOI: 10.1101/2025.03.12.642613

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