Article
Sorting of growth plate chondrocytes allows the isolation and characterization of cells of a defined differentiation status.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jun 2010
Belluoccio Daniele, Etich Julia, Rosenbaum Sabrina, Frie Christian, Grskovic Ivan, Stermann Jacek, Ehlen Harald, Vogel Simon, Zaucke Frank, von der Mark Klaus, Bateman John F, Brachvogel Bent
Abstract excerpt
Axial growth of long bones occurs through a coordinated process of growth plate chondrocyte proliferation and differentiation. This maturation of chondrocytes is reflected in a zonal change in gene expression and cell morphology from resting to proliferative, prehypertrophic, and hypertrophic cho...
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