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Apolipoprotein E is a marker of all chondrocytes in the growth plate resting zone

3 Mar 2025

Abstract excerpt

Abstract The resting zone (RZ) in mammalian growth plates is critical for maintaining and regulating chondrocyte turnover during longitudinal bone growth as a control tower and stem cell reservoir. Although recent lineage tracing studies have identified several markers for stem cells in the RZ, these markers only partially label chondrocytes in the RZ, suggesting that the resting chondrocytes (RCs) are a...

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PMID: 40025030
DOI: 10.1038/s41413-025-00407-2

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