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Article

Synthesizing genome-wide association studies and expression microarray reveals novel genes that act in the human growth plate to modulate height.

Human molecular genetics - 1 Dec 2012

Lui Julian C, Nilsson Ola, Chan Yingleong, Palmer Cameron D, Andrade Anenisia C, Hirschhorn Joel N, Baron Jeffrey

Abstract excerpt

Previous meta-analysis of genome-wide association (GWA) studies has identified 180 loci that influence adult height. However, each GWA locus typically comprises a set of contiguous genes, only one of which presumably modulates height. We reasoned that many of the causative genes within these loci influence height because they are expressed in and function in the growth plate, a cartilaginous structure that causes...

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Identifiers

PMID: 22914739
DOI: 10.1093/hmg/dds347
PMCID: PMC3490510

Genes

CNP
IHH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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