Article

Apolipoprotein E is a novel marker for chondrocytes in the growth plate resting zone

2024-08-05

Abstract excerpt

<title>Abstract</title> <p>The resting zone (RZ) in mammalian growth plates is critical for maintaining and regulating chondrocyte turnover during longitudinal bone growth as a control tower and stem cell reservoir. Although recent lineage tracing studies have identified several markers for stem cells in the RZ, these markers only partially label chondrocytes in the RZ, suggesting that the resting chondrocytes (R...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e690ba0f-ed6c-5299-8f59-d1a2e6d76b88
DOI: 10.21203/rs.3.rs-4656728/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Apolipoprotein E is a novel marker for chondrocytes in the growth plate resting zoneDOI 10.21203/rs.3.rs-4656728/v1Read

Apolipoprotein E is a marker of all chondrocytes in the growth plate resting zoneSemantic proximity Read

Human growth plates house resting zone sub-populations with features of quiescent stem cellsSemantic proximity Read

Single-Cell RNA-Sequencing Reveals the Skeletal Cellular Dynamics in Bone Repair and OsteoporosisSemantic proximity Read

Excess FGFR3 signaling in achondroplasia disrupts turnover of resting zone chondrocytes via CREB signaling.Semantic proximity Read

Single-cell transcriptomic analysis identifies a highly replicating Cd168+ skeletal stem/progenitor cell population in mouse long bonesSemantic proximity Read

Sorting of growth plate chondrocytes allows the isolation and characterization of cells of a defined differentiation status.Semantic proximity Read

Chondrogenic Enhancer Landscape of Limb and Axial Skeleton DevelopmentSemantic proximity Read

Early induction of a prechondrogenic population allows efficient generation of stable chondrocytes from human induced pluripotent stem cellsSemantic proximity Read

Single cell transcriptomics reveals chondrocyte differentiation dynamics <i>in vivo</i> and <i>in vitro</i>Semantic proximity Read

Fate of growth plate hypertrophic chondrocytes: Death or lineage extension?Semantic proximity Read

The Role of the Resting Zone in Growth Plate ChondrogenesisSemantic proximity Read

Gene Expression Profiling Reveals Similarities between the Spatial Architectures of Postnatal Articular and Growth Plate CartilageSemantic proximity Read