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Article

Risk assessment and transmission of fluoroquinolone resistance in drug-resistant pulmonary tuberculosis: a retrospective genomic epidemiology study.

Scientific reports - 24 Aug 2024

Nehru Vijayalakshmi Jawaharlal, Jose Vandakunnel Maria, Brammacharry Usharani, Ramachandra Venkateswari, Pradhabane Gunavathy, Mani Balasundaram Revathi, Vn Azger Dusthackeer, Muthaiah Muthuraj

Abstract excerpt

Fluoroquinolone resistance is a major challenge in treating Multidrug-Resistant Tuberculosis globally. The GenoType MTBDRsl Ver 2.0, endorsed by the WHO, was used to characterize fluoroquinolone resistance. The fluoroquinolone resistance rates in the MDR-TB, Rifampicin-Resistant TB, and non-MDR-TB were 33%, 16.5%, and 5.4%, respectively. The most common mutation found in fluoroquinolone-resistant isolates was...

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Identifiers

PMID: 39181942
DOI: 10.1038/s41598-024-70535-y
PMCID: PMC11344791

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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