Article
Molecular characterization of fluoroquinolone-resistant Mycobacterium tuberculosis clinical isolates from Shanghai, China.
Diagnostic microbiology and infectious disease - 1 Jul 2012
Zhu Cuiyun, Zhang Yongxin, Shen Yinzhong, Siu Gilman Kit Hang, Wu Wenjuan, Qian Xueqin, Deng Guilin, Xu Yan, Lau Ricky, Fan Xiaoyong, Zhang Wenhong, Lu Hongzhou, Yam Wing-Cheong
Abstract excerpt
China is one of the countries with the highest prevalence of fluoroquinolone-resistant (FQ(r)) Mycobacterium tuberculosis. Nevertheless, knowledge on the molecular characterization of the FQ(r)M. tuberculosis strains of this region remains very limited. This study was performed to investigate the frequencies and types of mutations present in FQ(r)M. tuberculosis clinical isolates collected in Shanghai, China. A...
Topics
- Antitubercular Agents
- China
- DNA Gyrase
- Drug Resistance, Bacterial
- Fluoroquinolones
- Genotype
- Humans
- Microbial Sensitivity Tests
- Mutation, Missense
- Mycobacterium tuberculosis