Article

Whole-brain functional connectivity predicts regional tau PET in preclinical Alzheimer’s disease

2024-04-03

Abstract excerpt

Preclinical Alzheimer’s disease (AD), characterized by the abnormal accumulation of amyloid prior to cognitive symptoms, presents a critical opportunity for early intervention. Past work has described functional connectivity changes in preclinical disease, yet the interplay between AD pathology and the functional connectome during this window remains unexplored. We applied connectome-based predictive modeling to i...

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Literature Corpus work: 742b94c8-eb20-5384-aa1a-7200a2da2eb5
DOI: 10.1101/2024.04.02.587791

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