Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Brain connectivity in neurodegenerative diseases--from phenotype to proteinopathy.

Nature reviews. Neurology - 1 Nov 2014

Pievani Michela, Filippini Nicola, van den Heuvel Martijn P, Cappa Stefano F, Frisoni Giovanni B

Abstract excerpt

Functional and structural connectivity measures, as assessed by means of functional and diffusion MRI, are emerging as potential intermediate biomarkers for Alzheimer disease (AD) and other disorders. This Review aims to summarize current evidence that connectivity biomarkers are associated with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Diffusion Magnetic Resonance Imaging
Share to Frontotemporal Dementia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Functional Neuroimaging

Share to Magnetic Resonance Imaging

Share to Neural Pathways

Share to Neurodegenerative Diseases

Share to Prodromal Symptoms

Source

Identifiers

PMID: 25287597
DOI: 10.1038/nrneurol.2014.178

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25287597-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Brain connectivity in neurodegenerative diseases--from phenotype to proteinopathy.PMID 25287597Read ↗

Human brain connectome profiles mediate the relationship between pathology burden and clinical phenotypes in Alzheimer's disease.Semantic proximity Read ↗

Structural and functional connectivity in tau mutation carriers: from presymptomatic to symptomatic frontotemporal dementia.Semantic proximity Read ↗

White matter dysfunction in Alzheimer’s disease is associated with disease-related transcriptomic signaturesSemantic proximity Read ↗

Subtypes of functional brain connectivity as early markers of neurodegeneration in Alzheimer’s diseaseSemantic proximity Read ↗

Alzheimer’s risk markers and resting-state dynamic functional connectivity: Cross-Sectional Findings from the AGUEDA StudySemantic proximity Read ↗

Network connectivity and local transcriptomic vulnerability underpin cortical atrophy progression in Parkinson's diseaseSemantic proximity Read ↗

Elucidating the neuropathological and molecular heterogeneity of amyloid-beta and tau in Alzheimer's disease through machine learning and transcriptomic integrationSemantic proximity Read ↗

Intrinsic connectivity of the human brain provides scaffold for tau aggregation in clinical variants of Alzheimer’s diseaseSemantic proximity Read ↗

Exploratory Correlation of The Human Structural Connectome with Non-MRI Variables in Alzheimer’s DiseaseSemantic proximity Read ↗

Multiplex connectome changes across the alzheimer’s disease spectrum using gray matter and amyloid dataSemantic proximity Read ↗

Amyloid-β and tau pathologies relate to distinctive brain dysconnectomics in preclinical autosomal dominant Alzheimer’s diseaseSemantic proximity Read ↗

Diagnosis and Prognosis of Alzheimer’s Disease Using Brain Morphometry and White Matter ConnectomesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.