Article

CD56neg CD16+ cells represent a distinct mature NK cell subset with altered phenotype and are associated with adverse clinical outcome upon expansion in AML.

2024-08-10

Abstract excerpt

<title>Abstract</title> CD56neg CD16+ Natural Killer (NK) cells have been reported to expand in chronic diseases and acute myeloid leukemia (AML). However, their biological role is still unclear. Using mass cytometry, spectral flow cytometry, bulk RNA-seq and <italic>in vitro</italic> assays, we characterized CD56neg CD16+ NK cells that expand in AML. We confirmed th...

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Literature Corpus work: 74041e61-cfee-550d-a3a0-4c279d6e8638
DOI: 10.21203/rs.3.rs-4656048/v1

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