Article
Human CD56bright NK Cells: An Update.
Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2016
Michel Tatiana, Poli Aurélie, Cuapio Angelica, Briquemont Benjamin, Iserentant Gilles, Ollert Markus, Zimmer Jacques
Abstract excerpt
Human NK cells can be subdivided into various subsets based on the relative expression of CD16 and CD56. In particular, CD56(bright)CD16(-/dim) NK cells are the focus of interest. They are considered efficient cytokine producers endowed with immunoregulatory properties, but they can also become cytotoxic upon appropriate activation. These cells were shown to play a role in different disease states, such as...
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