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Decoding NK Cell Subset Dysregulation in SARS-CoV-2 Infection: Phenotypic, Functional, and Transcriptomic Insights Into COVID-19 Pathogenesis.

Scandinavian journal of immunology - 1 Apr 2026

Sepúlveda Marlyn D, Cardona Maya Walter D, Zapata-Builes Wildeman, Velilla Paula A

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection significantly affects innate immune responses, particularly those of natural killer (NK) cells, which play an important role in antiviral defence. This review combines phenotypic, functional, and transcriptomic findings to explain the disruption of NK cell subsets in COVID-19. Flow cytometry studies have shown generalised lymphopenia and a...

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PMID: 41981866
DOI: 10.1111/sji.70115

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STAT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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