Article

Ovarian cancer-associated ascites accumulates NK lymphocytes with transcriptomic profile consistent with the immature/secretory CD56bright subtype.

2025-08-07

Abstract excerpt

Natural killer (NK) cells are important lymphocytes of the innate immunological defense against cancer. Based on their molecular and functional phenotypes NK cells are categorized in two main subtypes known as CD56 dim and CD56 bright , with distinct transcriptomes profiles. Additionally, transcriptomic alterations may arise in response to different stimuli or milieu, ultimately affecting the NK cell behavior. H...

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Literature Corpus work: 34c9f99d-d982-5a36-9517-117bc3420fa6
DOI: 10.22541/au.175457769.95283245/v1

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