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CD56 as a marker of an ILC1-like population with NK cell properties that is functionally impaired in AML

25 Nov 2019

Abstract excerpt

An understanding of natural killer (NK) cell physiology in acute myeloid leukemia (AML) has led to the use of NK cell transfer in patients, demonstrating promising clinical results. However, AML is still characterized by a high relapse rate and poor overall survival. In addition to conventional NKs that can be considered the innate counterparts of CD8 T cells, another family of innate lymphocytes has been...

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PMID: 31765481
DOI: 10.1182/bloodadvances.2018030478

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