Article
Synthetic mRNAs; Their Analogue Caps and Contribution to Disease
2021-07-19
Abstract excerpt
The structure of synthetic mRNAs as used in vaccination against cancer and infectious diseases contain specifically designed caps followed by sequences of the 5’ untranslated repeats of β-globin gene. The strategy for successful design of synthetic mRNAs by chemically modifying their caps aims to increase resistance to the enzymatic deccapping complex, offer a higher affinity for binding to the eukaryot...
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Identifiers and source
- Literature Corpus work
- 73f6b7c3-09ec-523f-9dd5-ac5bf55daba0
- DOI
- 10.20944/preprints202107.0402.v1
