Article
Synthetic mRNAs for manipulating cellular phenotypes: an overview.
New biotechnology - 25 Jan 2015
Quabius Elgar Susanne, Krupp Guido
Abstract excerpt
Availability of high quality synthetic mRNAs (syn-mRNAs) has enabled progress in their applications. Important structural features and quality requirements are discussed. Developments in the application of mRNA-mediated manipulation of cells are presented (i) mRNA-directed expression of antigens in dendritic cells for vaccination projects in oncogenesis, infectious disease and allergy prevention; (ii)...
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