Article

Pentagalloyl glucose Suppresses MSU Crystal–Induced Gout Inflammation and Arachidonic Acid Production In Vitro and In Vivo

2026-02-19

Abstract excerpt

<title>Abstract</title> <bold>Background</bold> Gout is an acute inflammatory arthritis triggered by monosodium urate (MSU) crystal deposition and activation of innate immune responses. In addition to inflammasome signaling, emerging evidence suggests that metabolic reprogramming of arachidonic acid (AA) pathways amplifies inflammatory responses during gout flares. However, the contribution of upstream fatt...

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Literature Corpus work: 736a0e8b-1b75-5f6e-9afb-de1bd348938b
DOI: 10.21203/rs.3.rs-8904164/v1

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