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Large-scale integration of omics and electronic health records to identify potential risk protein biomarkers and therapeutic drugs for cancer prevention

2024-05-31

Abstract excerpt

Identifying risk protein targets and their therapeutic drugs is crucial for effective cancer prevention. Here, we conduct integrative and fine-mapping analyses of large genome-wide association studies data for breast, colorectal, lung, ovarian, pancreatic, and prostate cancers, and characterize 710 lead variants independently associated with cancer risk. Through mapping protein quantitative trait loci (pQTL) for t...

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Literature Corpus work
7354a937-1854-542b-a682-ee25552a52b6
DOI
10.1101/2024.05.29.24308170
Open publication

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Large-scale integration of omics and electronic health records to identify potential risk protein biomarkers and therapeutic drugs for cancer preventionDOI 10.1101/2024.05.29.24308170
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