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Article

The circulating proteome and cancer risk: a systematic literature review and meta-analysis of 26 prospective studies with genetic validation.

EBioMedicine - 1 Feb 2026

Dillman Alison, An Haige, Huang Zhe, Chan Wing Ching, Blagden Sarah, Parsaeian Mahboubeh, Atkins Joshua R, Smith-Byrne Karl, Travis Ruth C

Abstract excerpt

BACKGROUND: Proteins have an integral role in cancer aetiology and inform cancer detection, treatment, and prognosis. While published data from prospective proteomic studies identifying early detection cancer risk markers have rapidly increased in the past five years, the landscape of evidence remains unclear. We aim to synthesise the evidence on circulating proteins and cancer risk. METHODS: We conducted a...

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Identifiers

PMID: 41512676
DOI: 10.1016/j.ebiom.2025.106117
PMCID: PMC12818075

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ITGA11

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

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