Article
Convergent proteogenomic evidence prioritises five causal proteins and new drug targets for major psychiatric disorders
2026-07-14
Abstract excerpt
Distinguishing causal biology from confounding or downstream consequences of psychiatric disorders remains a key barrier for drug development in psychiatry. We performed a large-scale proteogenomic investigation using a sequential triangulation framework integrating plasma proteomics, Mendelian randomisation, genetic colocalisation, transcriptomics, rare-variant analyses, and clinical phenotyping to identify causa...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 1b01aa91-60b5-5fb8-b1d6-4ab9e7a2afd4
- DOI
- 10.64898/2026.07.10.26357744