Article

Cross-tissue meta-analysis of blood and brain epigenome-wide association studies in Alzheimer’s disease

2022-04-12

Abstract excerpt

<h4>ABSTRACT</h4> We performed a meta-analysis of two large independent blood-based Alzheimer’s disease (AD) epigenome-wide association studies, the ADNI and AIBL studies, and identified 5 CpGs, mapped to the SPIDR, CDH6 genes, and intergenic regions, that were significantly associated with AD diagnosis. A cross-tissue analysis that combined these blood DNA methylation datasets with four additional methylation dat...

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Literature Corpus work: 733e5c06-e9e0-5654-aeb5-64b3d5b694dd
DOI: 10.1101/2022.04.11.22273748

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