Article

Activated thiol Sepharose-based proteomic approach to globally quantify protein oxidation

2019-02-14

Abstract excerpt

Reactive oxygen species (ROS) can act as second messengers for various signaling pathways, and abnormal oxidation contributes to multiple diseases, including cancer. Detecting and quantifying protein oxidation is crucial for a detailed understanding of redox signaling. We developed an Activated Thiol Sepharose (ATS)-based proteomic approach (ATSP) to globally quantify protein oxidation. ATSP can enrich for H 2 O...

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Literature Corpus work: 73101dc3-42e8-5dc4-bbae-aa477aa91619
DOI: 10.1101/549709

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