Article
Discovery of Diagnostic and Therapeutic Targets For Vascular Injury Induced By Methylglyoxal Using Proteomics
2021-05-20
Abstract excerpt
<h4>Background: </h4> Methylglyoxal, a byproduct of diabetes or the consumption of a high-carbohydrate diet, is associated with vascular injury; however, its molecular mechanisms remain unclear. We aimed to systematically characterize molecular profiles and offer unique insights into new disease pathways, thereby contributing to understanding the mechanisms and pathogenesis of vascular injury-related cardiovascula...
Topics
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- Advanced Glycation End Products research
- Epigenetics and DNA Methylation
- Histone Deacetylase Inhibitors Research
- Inflammatory mediators and NSAID effects
- Mitochondrial Function and Pathology
- Natural Antidiabetic Agents Studies
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Telomeres, Telomerase, and Senescence
Identifiers and source
- Literature Corpus work
- aa6138f1-44e9-5afc-8dd7-6dfe56a7317d
- DOI
- 10.21203/rs.3.rs-453632/v1
