Article

Integrated Spatial and Single-Nuclei Transcriptomic Analysis of Long Non-Coding RNAs in Alzheimer’s Disease

2024-10-28

Abstract excerpt

<h4>Background</h4> Long non-coding RNAs (lncRNAs) are critical regulators of physiological and pathological processes, with their dysregulation increasingly implicated in aging and Alzheimer’s disease (AD). To investigate the spatial and cellular distribution of lncRNAs in the aging brain, we leveraged published spatial transcriptomics (ST), single-nucleus RNA sequencing (snRNA-seq), and bulk RNA-seq datasets fr...

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Literature Corpus work: 72ae2ed3-9d8d-5428-a157-ea7be648b8bf
DOI: 10.1101/2024.10.27.620550

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