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Anti-tumor effect of IL-2 and TRAIL expressed by recombinant Salmonella: an immunotherapeutic proposal against bladder cancer by iNOS, Caspases activation and modulation of the immune system

2022-11-14

Abstract excerpt

IL-2 and TRAIL are therapeutic agents known for their antitumor role, but they can be cleared quickly by the body or be cytotoxic, compromising their function. To reverse this impasse, the synthesis of these agents by live bacteria directly in the tumor is a viable approach, due to bacteria’s preference to colonize tumor tissue. It happens because of the high nutrient grid in this microenvironment and possible esc...

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Literature Corpus work
728357f9-2671-5d31-8c5f-fcc080dea33b
DOI
10.21203/rs.3.rs-2256306/v1
Open publication

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Anti-tumor effect of IL-2 and TRAIL expressed by recombinant Salmonella: an immunotherapeutic proposal against bladder cancer by iNOS, Caspases activation and modulation of the immune systemDOI 10.21203/rs.3.rs-2256306/v1
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