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Engineered Salmonella expressing IL-18 as a therapeutic strategy for colorectal cancer

2026-06-30

Abstract excerpt

<title>Abstract</title> <p> Colorectal cancer (CRC) remains the second leading cause of cancer-related mortality worldwide, largely due to therapeutic resistance and metastatic progression. Novel strategies capable of targeting the tumor microenvironment and modulating key oncogenic pathways are urgently needed. In this study, we investigated the antitumor effect of attenuated <italic>Salmonella</italic> Typhi...

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Literature Corpus work: b152e32b-3259-5906-a79f-06eea0e3f7fa
DOI: 10.21203/rs.3.rs-10047645/v1

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