Article

Overview of The Current Progress of Facultative Anaerobic Bacteria in Cancer Biotherapy with TNF-α as Main Mechanism of Action

2021-04-05

Abstract excerpt

This review article focuses on the use of infectious bacteria as delivery tool for tumour necrosis factor α (TNF-α), a well-studied cytokine, in the context of immunotherapy for cancer treatment. The tumour targeting properties of certain bacteria strains has been known for decades as well as the tumour catabolizing effect of TNF-α. The combination of these two have been studied in murine models for various types...

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Literature Corpus work: 9761a6b8-563a-5efc-a6ce-c9d5c1e8a341
DOI: 10.1101/2021.04.03.21254792

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