Article

Detecting Differential Alternative Splicing in Mass Spectrometry-based Proteomics Data

2023-09-22

Abstract excerpt

<h4>Summary</h4> Alternative splicing can substantially diversify biological cell states and influence cellular function. The functional impact of splicing has to be estimated at protein level, typically by mass spectrometry (MS) -based proteomics. Although this technology measures increasingly large peptides sets, distinguishing isoform-specific peptides are rare, limiting detection and quantification of splicin...

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Literature Corpus work: 725b388e-a97a-5e5f-ba7e-eb4f5b6749a6
DOI: 10.1101/2023.09.19.558203

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