Article

PEXMap: A proteogenomic method for exon and isoform level mapping of mass spectrometry derived peptides

2026-05-04

Abstract excerpt

Alternative splicing (AS) expands transcriptome and proteome diversity by differentially combining exons or their splice variants. Although RNA-seq studies have uncovered transcriptomic variability, understanding the corresponding protein-level diversity remains limited. Mass spectrometry-based proteomics provides protein-level insights through MS/MS peptide annotations, which are mostly linked to gene/transcript...

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Literature Corpus work: 73a5a699-ea5d-52f0-a34d-2dd705c71634
DOI: 10.64898/2026.04.29.721330

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