Article

RNA sequencing depth guidelines for the study of alternative splicing

2024-10-13

Abstract excerpt

<h4>ABSTRACT</h4> A key parameter in the experimental design of RNA-seq projects is the choice of sequencing depth. Considering a limited budget, one needs to find a tradeoff between the number of samples and the sensitivity of the analysis, particularly concerning lowly expressed genes. While previous studies have proposed a lower bound for the comprehensive analysis of differential gene expression, for the anal...

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Literature Corpus work: 6afebf80-421f-53ef-89d0-004712eeca1c
DOI: 10.1101/2024.10.09.617406

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