APPRIS principal isoforms and MANE Select transcripts define reference splice variants.

Abstract excerpt

MOTIVATION: Selecting the splice variant that best represents a coding gene is a crucial first step in many experimental analyses, and vital for mapping clinically relevant variants. This study compares the longest isoforms, MANE Select transcripts, APPRIS principal isoforms, and expression data, and aims to determine which method is best for selecting biological important reference splice variants for...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Exons
• Share to Mice
• Share to Mutation