Article

Development of a Triplex FMCA Assay for Genotyping Three Genes, ADH1B, ADH1C, and ALDH2, Involved in Alcohol Metabolism

2026-02-10

Abstract excerpt

<title>Abstract</title> <p> Three functional single nucleotide variants (SNVs)‒ <italic>ALDH2</italic> rs671 (p.E504K), <italic>ADH1C</italic> rs698 (p.I350V), and <italic>ADH1B</italic> rs1229984 (p.R48H)‒are key genetic determinants of human alcohol metabolism. These variants significantly affect drinking behavior and are associated with liver disease and increased risks of several malignancies, includin...

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Literature Corpus work: 720cec03-c1f1-54c4-a549-62c11a4b446a
DOI: 10.21203/rs.3.rs-8635444/v1

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